Megaloblastic anaemias Essay Example | Topics and Well Written Essays - 750 words

Megaloblastic anaemias - Essay Example An absence of this factor is the most cause of pernicious (megaloblastic anemia).Children inherits this condition, when this condition happens low level of factors produce symptom of juvenile pernicious anemia in the children's less than age of 10. (Intelihealth). Nyhans syndrome or Lesch-Nhyan syndrome is a disroder that is caused the deficiency of an enzyme hypoxanthine-guanine phophoribosyltransferase(HGPRT). Lack of this enzyme, the human body to restrict the utilization of vitamin B12 leading to megaloblastic anemia. (Lesch-Nyhan Syndrome). Apart from cobalamin and folate deficiency, the molecular basis for the megaloblastic anemia is in the failure in the syntheisis and assembly of DNA. (Megaloblastic anemia). Other causes unclude cytotoxic drugs that interfere with DNA synthesis. Alcoholosim, preganancy, fish tapeworm infestation, faliure to replicate chromosomes due to lack of the nucletide thymidine and the disrution of intestinal flora due to antibiotic uses are some of the other causes of megaloblastic anemia. (Megaloblastic anemia). Anecdotal evidence suggests that in all cases of megaloblastic anaemia caused by deficiency of Vitamin B12 or folate, the patients will have an elevated MCV and a high HDW (Siemens, 2007). In cases of chemotherapy induced macrocytosis, the patients should have a normal or raised HDW (Siemens, 2007). ... The tests that are used to diagnose megaloblastic anemia primarily are routine tests like a blood test which included both complete blood count (hemoglobin and hemocrit) (Perinicous anemia). Very large oval blood cells and the presence of abnormally shaped neutrophils are indication of megaloblastic anemia. The physician enquires about complete medical history and physical examination, diagnostic procedure for the disorder. The physical exam include: 1) checking for pale or yellowish skin and a red and smooth tongue; 2) Listening of the heart to check the rapid heartbeat or murmur; 3) feeling the abdomen to check the size of the liver. (Pernicous anemia) Vital tests are also done to check the vitamin B12 level, folic acid. Homocysteine is high in anemia due to lack of cobalamin. The level of methymalonic acid is also high in anemia due to lack of vitamin B12 or folate. Other blood tests include the presence of intrinsic factor antibodies and parietal cell antibodies. The levels of bilirubin, potassium or cholesterol in the blood are also confirmed. The serum iron and the iron binding capacity are also checked. Reticulocytes count is also checked to conform if the bone marrow is producing RBCs at a proper rate. The reticulocyte number is low in patients suffering from Pernicious anemia. (Pernicous anemia) A schilling test is one of the very important tests that are being carried out in patients with this disorder. This test is done to detect the vitamin B12 absorption. Cobalamin levels are measured after the ingestion of radioactive Vitamin B12. In a normal scenario, the ileum absorbs more than the body and excreted out in urine but when a patient has megaloblastic anemia, he

Slide Presentation, Plastic Bags Assignment Example | Topics and Well Written Essays - 250 words

Slide Presentation, Plastic Bags - Assignment Example The second noteworthy facet was the insurmountable difference in the cost of recycling plastic bags and creating new bags. Jared Blumefeld noted that the cost of recycling is more that 125% the cost of creating new bags. Certainly, the government as well as private individuals cannot maintain the recycling drive for plastic bags at this ridiculous rate. If recycling then is not the answer what is? The third feature emphasizes a glimmer of hope for the stoppage and subsequent eradication of the dangers of the use of plastic. The creators of the presentation suggest that we can stop the use of plastic bags and replace the plastic with cloth. Besides the obvious advantage of being particularly recyclable one individual utilizing one cloth bag can replace the use of 288 plastic bags in one year. Therefore if every member of the population utilized cloth instead of plastic there would be a phenomenal removal of the dangers of plastic consumption in our lives. From the foregoing arguments one can conclude that the continued use of plastic bags are indeed detrimental to our lives as a consequence life as we know it today would be full of poison in the very near future unless we take the bull by the horn and make significant steps to removing the plastic from our daily lives. Thus, consistent with the findings as presented in the power point I recommend a complete 360 degrees turning from the use of plastic bags to a more positive alternative. Like the authors of this presentation I would like to reiterate the use of cloth instead of plastic and an outright ban of its use by the government. The author of this paper believes that in addition to the recommendations already made we as individuals and as a nation can plant trees to not only replenish the earth with positive substances but also to be used as material to create